KUSHAL KAPSE, BS, MS MRI Research Manager
Kushal Kapse, BS, MS, is MRI Research Manager for the Developing Brain Institute (DBI). Kushal joined DBI in 2015 and has played a pivotal role in its fetal and neonatal magnetic resonance imaging (MRI) research protocol development, harmonization and implementation efforts. He earned a BS in Mechanical Engineering and an MS in Biomedical Engineering from Texas Tech University, Lubbock. Kushal’s expertise includes MRI data acquisition, transfer and organization in adherence to HIPAA regulations. His research interests include learning novel acquisition and analyses techniques of MR images.
Address: 111 Michigan Ave. NW; Washington, D.C., 20010
Email: [email protected]
Department: MRI Lab
Research, Education and Innovation Week 2024 awards
Wu Y, Niforatos-Andescavage N, Wisner KL, Kapse K, Araki S, Mastracchio CE, Teramoto H, Kasper ML, du Plessis AJ, Limperopoulos C. "Prenatal SSRI exposure is associated with reduced regional fetal brain growth and cortical folding." Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024. (Certificate of Excellence awarded to lead author, Yao Wu. Clinical research: Career-Level Faculty Award.)
Recent publications & presentations
2024 | September
Pishghadam M, Ngwa JS, Wu Y, Kapse K, Haizler-Cohen L, Bulas D, Limperopoulos C, Andescavage NN. Single vs. multi-slice assessments of in vivo placental T2∗ measurements. Placenta. 2024 Sep 10;156:92-97. doi: 10.1016/j.placenta.2024.09.006. Epub ahead of print. PMID: 39293186
https://pubmed.ncbi.nlm.nih.gov/39293186
Kocher KM, Ngwa J, Kapse KJ, Bhattacharya S, Rossi C, Delot E, du Plessis A, Limperopoulos C, Andescavage N. Technical considerations for placental tissue processing and the subsequent impact on genome-wide DNA methylation analysis. Clinical Epigenetics. 2024 Sep 16;16(1):128. doi: 10.1186/s13148-024-01741-8. PMID: 39285447; PMCID: PMC11403961
https://pubmed.ncbi.nlm.nih.gov/39285447
Jacobwitz M, Kapse K, Ngwa J, De Asis-Cruz J, Wu Y, Govindan R, Donofrio MT, Wessel DL, du Plessis AJ, Limperopoulos C, Andescavage A. “In-Vivo Placental Volumes and Placental Growth Trajectories are Abnormal in Fetuses with Congenital Heart Disease.” International Federation of Placental Associations 2024 Conference. Montreal, Quebec. September 2024. (NIH travel award)
Jacobwitz M, Kapse K, Ngwa J, Donofrio MT, Wessel DL, du Plessis AJ, Limperopoulos C, Andescavage M. “Impaired Feto-Placental Growth in Congenital Heart Disease Detected Prenatally via Quantitative MRI.” International Federation of Placental Associations 2024 Conference. Montreal, Quebec. September 2024.
2024 | July
De Asis-Cruz J, Kalsi IA, Kapse K, Vezina G, Donofrio MT, Limperopoulos C. Decreased gray matter density in subcortical structures in newborns with complex congenital heart disease. NeoHeart 2024. (One of the top three conference abstracts.) New York, NY. July 2024.
Corn E, Andringa-Seed R, Williams ME, Arroyave-Wessel M, Tarud R, Vezina G, Podolsky RH, Kapse K, Limperopoulos C, Berl MM, Cure C, Mulkey SB. “Feasibility and success of a non-sedated brain MRI training protocol in 7-year-old children from rural and semi-rural Colombia.” Pediatric Radiology. 2024 Jul 6. doi: 10.1007/s00247-024-05964-y. Epub ahead of print. PMID: 38970708
https://pubmed.ncbi.nlm.nih.gov/38970708/
2024 | June
Weiner S, Wu Y, Kapse K, Vozar T, Cheng JJ, Murnick J, Henderson D, Teramoto H, Limperopoulos C, Andescavage N. "Prenatal maternal psychological distress during the COVID-19 pandemic and newborn brain development." JAMA Network Open. 2024 Jun 3;7(6):e2417924. doi: 10.1001/jamanetworkopen.2024.17924. PMID: 38900424
https://pubmed.ncbi.nlm.nih.gov/38900424
2024 | April
Damera SR, De Asis-Cruz J, Cook KM, Kapse K, Spoehr E, Murnick J, Basu S, Andescavage N, Limperopoulos C. "Regional homogeneity as a marker of sensory cortex dysmaturity in preterm infants." iScience. 2024 Apr 4;27(5):109662. doi: 10.1016/j.isci.2024.109662. PMID: 38665205; PMCID: PMC11043889
https://pubmed.ncbi.nlm.nih.gov/38665205/
Watson TT, Ottolini K, Basu S, Kapse K, Murnick J, Andescavage N, du Plessis A, Saulino P, Limperopoulos C. "Timing and growth failure in very premature infants and implications for brain development." Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.
Hui S, Andescavage N, Ngwa J, Kapse K, Kasper M, Saulino P, Limperopoulos C. "Brain metabolite concentrations in neonates with congenital heart disease before and after cardiac surgery." Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.
Hui S, Kapse K, Kasper M, Saulino P, Limperopoulos C, Andescavage N. "Brain metabolite concentrations in neonates of diabetic mothers." Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.
Pishghadam M, Haizler-Cohen L, Kapse K, Limperopoulos C, Niforatos-Andescavage N. "T2* weighted placental magnetic resonance imaging: a biomarker of placental dysfunction in pregnant..." Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.
Pishghadam M, Kapse K, Ngwa JS, Henderson D, Limperopoulos C, Niforatos-Andescavage N. "Non-invasive placental perfusion imaging in pregnant women exposed to COVID-19." Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.
Ottolini KM, Andescavage N, Basu SK, Kapse K, Watson T, Murnick J, du Plessis A, Limperopoulos C. "Type of intravenous lipid emulsion affects very preterm brain development." Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.
Chirumamilla VC, Hitchings L, Mulkey SB, Anwar T, Baker R, Maxwell L, De Asis Cruz J, Kapse K, Limperopoulos C, du Plessis AJ, Govindan RB. "Communications among Rich-club brain regions in term low-risk newborn EEG sources." Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.
Ngwa JS, Govindan R, Galla J, Kapse K, Basu S, Andescavage N, du Plessis AJ, Limperopoulos C. "The impact of conventional and high-frequency oscillatory ventilation on heart rate metrics in preterm infants." Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.
Weiner S, Wu Y, Vozar T, Ngwa JS, Kapse K, Henderson D, Andescavage N, Limperopoulos C. "It's all in the timing: effects of maternal anxiety on neurodevelopment." Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.
Jacobwitz M, Kapse K, Ngwa J, De Asis-Cruz J, Govindan R, Donofrio MT, Wessel D, du Plessis A, Limperopoulos C, Andescavage N. "In-vivo placental volumes and placental growth trajectories are abnormal in fetuses with congenital heart disease." Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.
Basu S, Hui SCN, Kapse K, Galla J, Andescavage N, Murnick J, du Plessis AJ, Limperopoulos C. "Cerebellar GABA and glutamate concentrations at term-age predicts cognitive deficits in preterm infants." Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.
Damera S, De Asis-Cruz J, Cook KM, Kapse K, Spoehr E, Basu SK, Andescavage N, Limperopoulos C. "Regional homogeneity tracks sensory cortex dysmaturity and predicts future risk of autism in preterm infants." Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.
Rich C, Kapse K, Ngwa J, Galla JT, Basu S, Ottolini K, Andescavage N, du Plessis A, Limperopoulos C. "Altered regional cerebral blood flow in preterm infants with patent ductus arteriosus." Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.
Cruz J, Kim JH, Cook KM, Teramoto H, Mastracchio CE, Kapse KJ, Andescavage N, Limperopoulos C. "Associations between fetal hippocampal functional connectivity and maternal psychopathology." Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.
2024 | February
Chirumamilla VC, Hitchings L, Mulkey SB, Anwar T, Baker R, Larry Maxwell G, De Asis-Cruz J, Kapse K, Limperopoulos C, du Plessis A, Govindan RB. "Association of brain functional connectivity with neurodevelopmental outcomes in healthy full-term newborns." Clin Neurophysiol. 2024 Feb 15;160:68-74. doi: 10.1016/j.clinph.2024.02.009. Epub ahead of print. PMID: 38412745
https://pubmed.ncbi.nlm.nih.gov/38412745/
2024 | January
Andescavage N, Lu YC, Wu Y, Kapse K, Keller J, Von Kohorn I, Afifi A, Vezina G, Henderson D, Wessel DL, du Plessis AJ, Limperopoulos C. "Intrauterine exposure to SARS-CoV-2 infection and early newborn brain development." Cereb Cortex. 2024 Jan 31;34(2):bhae041. doi: 10.1093/cercor/bhae041. PMID: 38385890
https://pubmed.ncbi.nlm.nih.gov/38385890/
2023 | October
Andescavage NN, Pradhan S, Gimovsky AC, Kapse K, Donofrio MT, Cheng JJ, Sharker Y, Wessel D, du Plessis AJ, Limperopoulos C. Magnetic Resonance Spectroscopy of Brain Metabolism in Fetuses With Congenital Heart Disease. J Am Coll Cardiol. 2023 Oct 17;82(16):1614-1623. doi: 10.1016/j.jacc.2023.08.013. PMID: 37821172
https://pubmed.ncbi.nlm.nih.gov/37821172/
2023 | May
Saeed H, Lu YC, Andescavage N, Kapse K, Andersen NR, Lopez C, Quistorff J, Barnett S, Henderson D, Bulas D, Limperopoulos C. Influence of maternal psychological distress during COVID-19 pandemic on placental morphometry and texture. Sci Rep. 2023 May 10;13(1):7374. doi: 10.1038/s41598-023-33343-4. PMID: 37164993; PMCID: PMC10172401
https://pubmed.ncbi.nlm.nih.gov/37164993/
2023 | April
Kim JH, De Asis-Cruz J, Kapse K, Limperopoulos C. Systematic evaluation of head motion on resting-state functional connectivity MRI in the neonate. Hum Brain Mapp. 2023 Apr 1;44(5):1934-1948. doi: 10.1002/hbm.26183. Epub 2022 Dec 28. PMID: 36576333; PMCID: PMC9980896.
https://pubmed.ncbi.nlm.nih.gov/36576333/
Weiner S, Wu Y, Kapse K, Krishnamurthy D, Limperopoulos C. Elevated maternal anxiety during the COVID-19 pandemic alters newborn hippocampal and amygdala development. Children’s National Hospital 13th Annual Research, Education and Innovation Week. Washington, D.C. April 2023. (Award-winning poster: Clinical research: Graduate student)
Lundberg RS, Basu SK, Andescavage N, Pradhan S, Ottolini KM, Kapse KJ, Limperopoulos C. Early parenteral lipid intake improves cerebellar neurometabolism in preterm infants. Children’s National Hospital 13th Annual Research, Education and Innovation Week. Washington, D.C. April 2023. (Award-winning poster: Clinical research: Fellows/residents)
Andescavage N, Bullen T, Liggett M, Barnett SD, Kapse A, Kapse K, Ahmadzia H, Vezina G, Quistorff J, Lopez C, du Plessis A, Limperopoulos C. “Impaired in vivo feto-placental development is associated with neonatal neurobehavioral outcomes.” Pediatric Research. 2023 Apr;93(5):1276-1284. doi: 10.1038/s41390-022-02340-0. Epub 2022 Nov 5. PMID: 36335267; PMCID: PMC10147575
https://pubmed.ncbi.nlm.nih.gov/36335267/
2023 | March
Chirumamilla VC, Hitchings L, Mulkey SB, Anwar T, Baker R, Larry Maxwell G, De Asis-Cruz J, Kapse K, Limperopoulos C, du Plessis A, Govindan RB. Functional brain network properties of healthy full-term newborns quantified by scalp and source-reconstructed EEG. Clin Neurophysiol. 2023 Mar;147:72-80. doi: 10.1016/j.clinph.2023.01.005. Epub 2023 Jan 23. PMID: 36731349; PMCID: PMC9975070
https://pubmed.ncbi.nlm.nih.gov/36731349/
2022 | April
Wu Y, Espinosa KM, Barnett SD, Kapse A, Quistorff JL, Lopez C, Andescavage N, Pradhan S, Lu YC, Kapse K, Henderson D, Vezina G, Wessel D, du Plessis AJ, Limperopoulos C. Association of elevated maternal psychological distress, altered fetal brain, and offspring cognitive and social-emotional outcomes at 18 months. JAMA Netw Open. 2022 Apr 1;5(4):e229244. doi: 10.1001/jamanetworkopen.2022.9244. PMID: 35486403; PMCID: PMC9055453.
https://pubmed.ncbi.nlm.nih.gov/35486403/
2022 | January
Largent A, De Asis-Cruz J, Kapse K, Barnett SD, Murnick J, Basu S, Andersen N, Norman S, Andescavage N, Limperopoulos C. Automatic brain segmentation in preterm infants with post-hemorrhagic hydrocephalus using 3D Bayesian U-Net. Hum Brain Mapp. 2022 Jan 13. doi: 10.1002/hbm.25762. Epub ahead of print. PMID: 35023255
https://pubmed.ncbi.nlm.nih.gov/35023255/
Basu SK, Pradhan S, Barnett SD, Mikkelsen M, Kapse KJ, Murnick J, Quistorff JL, Lopez CA, du Plessis AJ, Limperopoulos C. Regional differences in gamma-aminobutyric acid and glutamate concentrations in the healthy newborn brain. AJNR Am J Neuroradiol. 2022 Jan;43(1):125-131. doi: 10.3174/ajnr.A7336. Epub 2021 Nov 11. PMID: 34764083
https://pubmed.ncbi.nlm.nih.gov/34764083/