SUDEEPTA K. BASU, M.D. Attending Neonatologist

Sudeepta K. Basu, M.D., is an attending neonatologist and investigates early neuroimaging markers of brain injury in preterm newborns. Dr. Basu employs advanced magnetic resonance spectroscopy to investigate the metabolic and functional profile of the developing brain in preterm infants. In particular, he focuses on novel neuroimaging techniques to estimate the concentration of GABA, a vital neurotransmitter, in preterm brains (Project MAGIC study) under the mentorship of Catherine Limperopoulos, Ph.D., at the Developing Brain Institute at Children’s National. Dr. Basu also investigates metabolic and neuroimaging characteristics of near-term infants who suffered from perinatal birth asphyxia (HIE).

Address: 111 Michigan Ave. NW; Washington, D.C., 20010
Email: [email protected]
Department: MRI Lab

Research, Education and Innovation Week 2024 awards

Kocher K, Ngwa J, Galla JT, Basu SK, Ottolini K, Andescavage N, du Plessis A, Limperopoulos C. Early epigenetic biomarkers of accelerated aging in extremely versus very preterm infants. Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024. (Certificate of Excellence awarded to lead author, Kristen Kocher. Basic Science: Fellow Award.)

RECENT PUBLICATIONS & PRESENTATIONS

2024 | April

Damera SR, De Asis-Cruz J, Cook KM, Kapse K, Spoehr E, Murnick J, Basu S, Andescavage N, Limperopoulos C. Regional homogeneity as a marker of sensory cortex dysmaturity in preterm infants. iScience. 2024 Apr 4;27(5):109662. doi: 10.1016/j.isci.2024.109662. PMID: 38665205; PMCID: PMC11043889
https://pubmed.ncbi.nlm.nih.gov/38665205/

Reze C, Andescavage NN, Basu S, Galla J, Limperopoulos C, Wu Y. Sex differences in pituitary gland volume in preterm infants. Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.

Watson TT, Ottolini K, Basu S, Kapse K, Murnick J, Andescavage N, du Plessis A, Saulino P, Limperopoulos C. Timing and growth failure in very premature infants and implications for brain development. Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.

Ottolini KM, Andescavage N, Basu SK, Kapse K, Watson T, Murnick J, du Plessis A, Limperopoulos C. Type of intravenous lipid emulsion affects very preterm brain development. Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.

Cook KM, De Asis-Cruz J, Andescavage N, Saulino P, Basu SK, du Plessis AJ, Limperopoulos C. Greater exposure to opioid pain medications in the NICU is associated with hyperconnectivity of the thalamus and cerebellum in infants born prematurely. Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.

Ngwa JS, Govindan R, Galla J, Kapse K, Basu S, Andescavage N, du Plessis AJ, Limperopoulos C. The impact of conventional and high-frequency oscillatory ventilation on heart rate metrics in preterm infants. Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.

Basu S, Hui SCN, Kapse K, Galla J, Andescavage N, Murnick J, du Plessis AJ, Limperopoulos C. Cerebellar GABA and glutamate concentrations at term-age predicts cognitive deficits in preterm infants. Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.

Spurney G, Gala J, Basu S, Ottolini K, Andescavage N, du Plessis A, Limperopoulos C. High prevalence of low dietary intake of choline in mothers of preterm infants. Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.

Damera S, De Asis-Cruz J, Cook KM, Kapse K, Spoehr E, Basu SK, Andescavage N, Limperopoulos C. Regional homogeneity tracks sensory cortex dysmaturity and predicts future risk of autism in preterm infants. Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.

Rich C, Kapse K, Ngwa J, Galla JT, Basu S, Ottolini K, Andescavage N, du Plessis A, Limperopoulos C. Altered regional cerebral blood flow in preterm infants with patent ductus arteriosus. Children’s National Hospital 14th Annual Research, Education and Innovation Week. Washington, D.C. April 2024.

2023 | November

Cook KM, De Asis-Cruz J, Kim JH, Basu SK, Andescavage N, Murnick J, Spoehr E, Liggett M, du Plessis AJ, Limperopoulos C. Experience of early-life pain in premature infants is associated with atypical cerebellar development and later neurodevelopmental deficits. BMC Med. 2023 Nov 14;21(1):435. doi: 10.1186/s12916-023-03141-w. PMID: 37957651
https://pubmed.ncbi.nlm.nih.gov/37957651/

Basu SK, Kapse KJ, Murnick J, Pradhan S, Spoehr E, Zhang A, Andescavage N, Nino G, du Plessis AJ, Limperopoulos C. Impact of bronchopulmonary dysplasia on brain GABA concentrations in preterm infants: Prospective cohort study. Early Hum Dev. 2023 Nov;186:105860. doi: 10.1016/j.earlhumdev.2023.105860. Epub 2023 Sep 21. PMID: 37757548
https://pubmed.ncbi.nlm.nih.gov/37757548/

2023 | April

Lundberg RS, Basu SK, Andescavage N, Pradhan S, Ottolini KM, Kapse KJ, Limperopoulos C. Early parenteral lipid intake improves cerebellar neurometabolism in preterm infants. Children’s National Hospital 13th Annual Research, Education and Innovation Week. Washington, D.C. April 2023. (Award-winning poster: Clinical research: Fellows/residents)

2022

Largent A, De Asis-Cruz J, Kapse K, Barnett SD, Murnick J, Basu S, Andersen N, Norman S, Andescavage N, Limperopoulos C.
Automatic brain segmentation in preterm infants with post-hemorrhagic hydrocephalus using 3D Bayesian U-Net. Hum Brain Mapp. 2022 Jan 13. doi: 10.1002/hbm.25762. Epub ahead of print. PMID: 35023255
https://pubmed.ncbi.nlm.nih.gov/35023255/

Basu SK, Pradhan S, Barnett SD, Mikkelsen M, Kapse KJ, Murnick J, Quistorff JL, Lopez CA, du Plessis AJ, Limperopoulos C.
Regional differences in gamma-aminobutyric acid and glutamate concentrations in the healthy newborn brain. AJNR Am J Neuroradiol. 2022 Jan;43(1):125-131. doi: 10.3174/ajnr.A7336. Epub 2021 Nov 11. PMID: 34764083
https://pubmed.ncbi.nlm.nih.gov/34764083/