Katherine M. Ottolini, M.D.
Attending, Neonatal-Perinatal Medicine
Katherine M. Ottolini, M.D., is attending, Neonatal-Perinatal Medicine, at Children’s National Hospital, and she has collaborated with the Developing Brain Institute (DBI) on research since 2018. Since returning to DBI at Children’s National in September 2022, Dr. Ottolini remains focused on using advanced MRI techniques to evaluate the effects of early nutritional interventions on preterm brain development, with the aim of optimizing growth and neurodevelopmental outcomes for this vulnerable population.
Key Studies
| November 2025 | Ottolini KM, Basu SK, Ngwa J, Kapse K, Murnick J, Cook KM, Wu Y, Watson TT, du Plessis AJ, Limperopoulos C, Andescavage N. Donor Human Milk and Structural Brain Development in Very Preterm Infants. Pediatric Research. 2025 Nov 1:10.1038/s41390-025-04539-3. doi: 10.1038/s41390-025-04539-3. Epub ahead of print. PMID: 41174153; PMCID: PMC12959636 | view |
| December 2024 | Ottolini KM, Ngwa J, Basu SK, Kapse K, Liggett M, Murnick J, Limperopoulos C, Andescavage N. Brain Development Using a Multicomponent Intravenous Lipid Emulsion in Preterm Infants. BMC Pediatrics. 2024 Dec 30;24(1):847. doi: 10.1186/s12887-024-05330-9. PMID: 39736580; PMCID: PMC11687010 | view |
Date: April 2022
Seed M, Limperopoulos C. In Utero Brain Growth Matters for Fetuses With Congenital Heart Disease. Circulation. 2022 Apr 12;145(15):1120-1122. doi: 10.1161/CIRCULATIONAHA.122.058683. Epub 2022 Apr 11. PMID: 35404677
View: https://pubmed.ncbi.nlm.nih.gov/35404677
Date: January 2010
Limperopoulos C, Tworetzky W, McElhinney DB, Newburger JW, Brown DW, Robertson RL Jr, Guizard N, McGrath E, Geva J, Annese D, Dunbar-Masterson C, Trainor B, Laussen PC, du Plessis AJ. Brain Volume and Metabolism in Fetuses With Congenital Heart Disease: Evaluation With Quantitative Magnetic Resonance Imaging and Spectroscopy. Circulation. 2010 Jan 5;121(1):26-33. doi: 10.1161/CIRCULATIONAHA.109.865568. Epub 2009 Dec 21. PMID: 20026783; PMCID: PMC2819908
View: https://pmc.ncbi.nlm.nih.gov/articles/PMC2819908
Date: February 2024
Wu Y, De Asis-Cruz J, Limperopoulos C. Brain Structural and Functional Outcomes in the Offspring of Women Experiencing Psychological Distress During Pregnancy. Molecular Psychiatry. 2024 Jul;29(7):2223-2240. doi: 10.1038/s41380-024-02449-0. Epub 2024 Feb 28. PMID: 38418579; PMCID: PMC11408260
View: https://pubmed.ncbi.nlm.nih.gov/38418579
Date: April 2022
Wu Y, Espinosa KM, Barnett SD, Kapse A, Quistorff JL, Lopez C, Andescavage N, Pradhan S, Lu YC, Kapse K, Henderson D, Vezina G, Wessel D, du Plessis AJ, Limperopoulos C. Association of Elevated Maternal Psychological Distress, Altered Fetal Brain, and Offspring Cognitive and Social-Emotional Outcomes at 18 Months. JAMA Network Open. 2022 Apr 1;5(4):e229244. doi: 10.1001/jamanetworkopen.2022.9244. PMID: 35486403; PMCID: PMC9055453
View: https://pubmed.ncbi.nlm.nih.gov/35486403