Advanced Physiological Signals Processing Lab

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The Advanced Physiological Signals Processing Lab, directed by Rathinaswamy Bhavanandhan (RB) Govindan, Ph.D., MS, is expanding a unique library of analytic tools to automate analyses of large datasets of physiologic systems. In recent years, Dr. Govindan has developed novel heart-rate variability measures that more accurately predict the severity of autonomic impairment in sick infants than traditional measures. He collaborated with Adré J. du Plessis, M.B.Ch.B., to file a provisional patent and to establish experiments in experimental models to validate Dr. Govindan’s novel neuromonitoring tools. Dr. Govindan's team currently works on real-time characterization of physiological signals to help with goal-oriented clinical decision-making.

Lab Focus Area

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Head_and_Shoulders_Rounded_Corners_no_image_rev10June26-20260611153158

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Head_and_Shoulders_Rounded_Corners_no_image_rev10June26-20260611153158

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Our Research

Our goal is to enhance understanding of the subtle signs and signals that predict which high-risk fetuses or critically ill newborns will go onto do develop brain injury. Our team accomplishes this by studying tell-tale patterns in physiological signals, by developing non-invasive tools to measure these patterns in children, and by translating experimental discoveries to the bedside to benefit fetuses and newborns.