Kelsey Christoffel, M.D.
Prenatal-Neonatal Neurologist
Kelsey Christoffel, M.D., is a Prenatal-Neonatal Neurologist at Children’s National Hospital. Dr. Christoffel works with the Developing Brain Institute to study brain development and connectivity in congenital brain anomalies. Her goal is to find quantitative fetal brain imaging markers to better predict neurodevelopmental outcomes in conditions where prognostic accuracy is currently lacking.
Key Studies
| March 2026 | Cook KM, De Asis-Cruz J, Kapse K, Christoffel K, McDermott C, Andescavage N, Limperopoulos C. Prenatal Experience of Greater Neighborhood Disadvantage Is Associated With Altered Fetal Volumetric Brain Growth in Utero. Cerebral Cortex. 2026 Mar 3;36(3):bhag017. doi: 10.1093/cercor/bhag017. PMID: 41772840 | view |
| January 2025 | Christoffel K, De Asis Cruz J, Cook KM, Kapse K, Andescavage N, Basu S, Limperopoulos C, du Plessis A. Third Trimester Development of Central Autonomic Network Connectivity Is Altered in an Extrauterine Environment. Neonatology. 2025 Jan 2:1-20. doi: 10.1159/000543277. Epub ahead of print. PMID: 39746339 | view |
Date: April 2022
Seed M, Limperopoulos C. In Utero Brain Growth Matters for Fetuses With Congenital Heart Disease. Circulation. 2022 Apr 12;145(15):1120-1122. doi: 10.1161/CIRCULATIONAHA.122.058683. Epub 2022 Apr 11. PMID: 35404677
View: https://pubmed.ncbi.nlm.nih.gov/35404677
Date: January 2010
Limperopoulos C, Tworetzky W, McElhinney DB, Newburger JW, Brown DW, Robertson RL Jr, Guizard N, McGrath E, Geva J, Annese D, Dunbar-Masterson C, Trainor B, Laussen PC, du Plessis AJ. Brain Volume and Metabolism in Fetuses With Congenital Heart Disease: Evaluation With Quantitative Magnetic Resonance Imaging and Spectroscopy. Circulation. 2010 Jan 5;121(1):26-33. doi: 10.1161/CIRCULATIONAHA.109.865568. Epub 2009 Dec 21. PMID: 20026783; PMCID: PMC2819908
View: https://pmc.ncbi.nlm.nih.gov/articles/PMC2819908
Date: February 2024
Wu Y, De Asis-Cruz J, Limperopoulos C. Brain Structural and Functional Outcomes in the Offspring of Women Experiencing Psychological Distress During Pregnancy. Molecular Psychiatry. 2024 Jul;29(7):2223-2240. doi: 10.1038/s41380-024-02449-0. Epub 2024 Feb 28. PMID: 38418579; PMCID: PMC11408260
View: https://pubmed.ncbi.nlm.nih.gov/38418579
Date: April 2022
Wu Y, Espinosa KM, Barnett SD, Kapse A, Quistorff JL, Lopez C, Andescavage N, Pradhan S, Lu YC, Kapse K, Henderson D, Vezina G, Wessel D, du Plessis AJ, Limperopoulos C. Association of Elevated Maternal Psychological Distress, Altered Fetal Brain, and Offspring Cognitive and Social-Emotional Outcomes at 18 Months. JAMA Network Open. 2022 Apr 1;5(4):e229244. doi: 10.1001/jamanetworkopen.2022.9244. PMID: 35486403; PMCID: PMC9055453
View: https://pubmed.ncbi.nlm.nih.gov/35486403